|Calculated MW||101128 Da|
|Immunogen||Synthetic peptide: C-terminal region of human CD167.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Epithelial discoidin domain-containing receptor 1, Epithelial discoidin domain receptor 1, 188.8.131.52, CD167 antigen-like family member A, Cell adhesion kinase, Discoidin receptor tyrosine kinase, HGK2, Mammary carcinoma kinase 10, MCK-10, Protein-tyrosine kinase 3A, Protein-tyrosine kinase RTK-6, TRK E, Tyrosine kinase DDR, Tyrosine-protein kinase CAK, CD167a, DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE|
|Target/Specificity||Rabbit anti Human CD167 antibody detects an epitope within the C-terminal of human CD167, a Discoidin Domain Receptor (DDR) also known as DDR1. CD167, a receptor for collagen, is widely expressed in normal and transformed epithelial cells, and may regulate cell adhesion, proliferation and extracellular matrix remodelling.CD167 is a ~125 kDa protein which is partially processed into a 62 kDa membrane-anchored beta-subunit and a 54 kDa soluble alpha-subunit. This process, also termed shedding, is significantly enhanced upon CD167 activation.CD167 has been demonstrated to be a direct transcriptional target of the p53 tumour suppressor gene, and is significantly over-expressed in breast, ovarian, oesophageal, and paediatric brain tumours.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human CD167 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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