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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti Human ErbB4 Antibody    

Anti Human ErbB4 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC-P - Anti Human ErbB4 Antibody  ABD13269
    Staining of formalin fixed, paraffin embedded human glomerulus with Rabbit anti Human ErbB4
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15303
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 146808 Da
Additional Information
Immunogen Synthetic peptide: Internal domain of human ErbB4.
Shelf Life 18 months from date of despatch.
Gene ID 2066
Other Names Receptor tyrosine-protein kinase erbB-4,, Proto-oncogene-like protein c-ErbB-4, Tyrosine kinase-type cell surface receptor HER4, p180erbB4, ERBB4 intracellular domain, 4ICD, E4ICD, s80HER4, ERBB4, HER4
Target/Specificity ABD13269 detects an epitope within the internal region of human ErbB4, a transmembrane protein which is a member of the epidermal growth factor receptor subfamily. ErbB4 is activated by a number of factors including neuregulins and betacellulin, which leads to the cleavage of a 120kD ectodomain fragment by TACE. In the cell, the remaining 80kD fragment of ErbB4 is internalised and cleaved by gamma-secretase. This fragment translocates to the nucleus and induces cell proliferation and differentiation.ErbB4 is important in embryonic development, and mutations to its gene have been associated with cancer.
Preservative & Stabilisers 0.1%Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human ErbB4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13269
(40 western blots)
Availability: Inquire
Bulk Size
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