|Calculated MW||250794 Da|
|Immunogen||Synthetic peptide: Internal domain of human WNK1.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Serine/threonine-protein kinase WNK1, 188.8.131.52, Erythrocyte 65 kDa protein, p65, Kinase deficient protein, Protein kinase lysine-deficient 1, Protein kinase with no lysine 1, hWNK1, WNK1, HSN2, KDP, KIAA0344, PRKWNK1|
|Target/Specificity||ABD13270 detects an epitope within the internal region (IN) of WNK1, a 250kD cytoplasmic serine/threonine kinase which regulates the activity of a number of ion transporters, and thus has an important role in blood pressure and ion homeostasis. Alternative splicing of WNK1 produces a kidney-specific short form that lacks a kinase domain, KS-WNK1, and a more ubiquitous long form, L-WNK1. WNK1 and WNK4 have been identified as the dysregulated genes in Gordon’s syndrome (pseudohypoaldosteronism type 2 [PHA2]) which affects salt homeostasis by the kidney.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human WNK1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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