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Anti Human UCH-L3 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC-P - Anti Human UCH-L3 Antibody  ABD13272
    Staining of formalin fixed, paraffin embedded human testis with Rabbit anti Human UCH-L3
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P15374
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 26183 Da
Additional Information
Immunogen A synthetic peptide corresponding to an internal domain of human UCH-L3, conjugated to KLH.
Shelf Life 18 months from date of despatch.
Gene ID 7347
Other Names Ubiquitin carboxyl-terminal hydrolase isozyme L3, UCH-L3,, Ubiquitin thioesterase L3, UCHL3
Target/Specificity Rabbit anti Human UCH-L3 antibody detects an epitope within the internal domain of human ubiquitin C-terminal hydrolase L3 (UCH-L3), a ~26 kDa thiol protease that hydrolyses a peptide bond in ubiquitin and nedd8. UCH-L3 and the closely related UCH-L1 are thought to recycle ubiquitin to maintain pools of monomeric ubiquitin necessary for proteolysis. UCH-L1 and UCH-L3 have been shown to have separate and overlapping functions in the maintanence of neurons of the gracile tract, nucleus tractus solitarius (NTS) and area postrema (AP). UCH-L3 defective mice have a learning deficit compared to wild type littermates, and significantly increased working memory errors (Woodet al2005).
Preservative & Stabilisers 0.09%Sodium Azide
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human UCH-L3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13272
(40 western blots)
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