|Calculated MW||43031 Da|
|Immunogen||Synthetic peptide corresponding to the C-terminal region of rat connexin 43 (CT).|
|Shelf Life||12 months from date of despatch.|
|Other Names||Gap junction alpha-1 protein, Connexin-43, Cx43, Gap junction 43 kDa heart protein, Gja1, Cxn-43|
|Target/Specificity||ABD13275 recognises rat connexin43, a 43kDa member of the Alpha-type (group II) subfamily of the connexins. It is a component of gap junctions, the small channels linking the cytoplasm of adjacent cells and enabling signalling through the transfer of ions and metabolites. Phosphorylation of Connexin 43 at serine 368 regulates the permeability of the gap junction. Connexin 43 is the major protein of gap junctions in the heart, essential to synchronised contractions. It is also crucial in embryonic development and is associated with epilepsy.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Connexin 43 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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