|Calculated MW||42518 Da|
|Immunogen||Synthetic peptide: N-terminal domain of human SphK1, conjugated to KLH.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Sphingosine kinase 1, SK 1, SPK 1, 188.8.131.52, SPHK1, SPHK, SPK|
|Target/Specificity||ABD13276 detects an epitope within the N-terminal region human SphK1, also known sphingosine kinase 1. SphK1 catalyzes the phosphorylation of sphingosine 1-phosphate; an important lipid mediator with multiple functions. In light of this, SphK1 has been implicated in regulation of Ca2+ homoeostasis, inflammation, immunity and cancer growth. However, its central function is thought to be in the development of the cardiovascular and central nervous system. SphK1 has a molecular weight of 42kD.|
|Preservative & Stabilisers||0.1% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human SPHK1 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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