|Calculated MW||54278 Da|
|Immunogen||14 amino acid peptide sequence near the carboxy terminus of human IRF7.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Interferon regulatory factor 7, IRF-7, IRF7|
|Target/Specificity||Rabbit anti IRF7 antibody detects an epitope within the C-terminal (CT) of human interferon regulatory factor 7 (IRF7), a ~54 kDa transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production.Multiple IRF7 transcript variants have been identified, although their individual functions have not yet been established.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti IRF7 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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