|Application ||WB, E|
|Calculated MW||134277 Da|
|Immunogen||Synthetic peptide corresponding to amino acids 1189-1199 of human EGF receptor protein.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Epidermal growth factor receptor, 184.108.40.206, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EGFR, ERBB, ERBB1, HER1|
|Target/Specificity||Rabbit anti Human epidermal growth factor receptor antibody recognizes human epidermal growth factor receptor (EGFR), also known as Proto-oncogene c-ErbB-1. EGFR is a 1210 amino acid single pass type 1 ~170kDa transmembrane glycoprotein which is a member of the ErbB family of receptor tyrosine kinases. EGFR is the cell surface receptor for members of the EGF family, and functions in early embryonic development and in the renewal of stem cells in tissues such as the skin, liver and gut (Nautiyalet al.2010).Mutations to EGFR have been found in many human carcinomas including breast, brain, lung, and colon(Garcia de Palazzo et al.1993).|
|Preservative & Stabilisers||0.01% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human EGF Receptor Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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