|Application ||WB, E, IP|
|Calculated MW||22073 Da|
|Immunogen||Full length human p27 protein|
|Shelf Life||18 months from date of despatch.|
|Other Names||Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, CDKN1B, KIP1|
|Target/Specificity||ABD13291 detects p27, a member of the Kip/Cip family of proteins which is also known as p27kip1. p27 is a cyclin dependent kinase inhibitor (CKI) which controls G1/S phase transition in the cell cycle. p27 prevents cell cycle progression by inhibiting the activity of cyclin E-Cdk2 and cyclin D-Cdk4/6, thus preventing E2F activation and S phase progression. Low p27 levels and/or cytosolic mis-localisation have been associated with the development of lung, breast, colon, oesophagus, and prostate tumours.|
|Preservative & Stabilisers||0.01% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human p27/kip1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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