|Application ||WB, IHC-P, E, Func|
|Calculated MW||22931 Da|
|Immunogen||Recombinant human CNTF(PHP173)|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Ciliary neurotrophic factor, CNTF, CNTF|
|Target/Specificity||This product recognises human CNTF (ciliary neurotrophic factor), a 200 amino acid homodimeric neurotrophic and differentiation factor of the CNTF family, which supports the survival and differentiation of several motor neuron types within the nervous system, but also affects other target tissues, including skeletal muscle (Vergara, C. & Ramirez, B.), glial cells, hepatocytes and embryonic stem cells.CNTF mainly signals through binding to a receptor complex consisting of a CNTFRa subunit, two beta components, gp130 and LIFR, resulting ultimately in the activation of JAK/STAT signalling pathway, but CNTF has also been shown to bind to the receptor for interleukin-6 (IL-6R).|
|Preservative & Stabilisers||None present|
|Storage||Store at +4oC or at -20oC if preferred.|
|Precautions||Anti Human CNTF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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