|Application ||WB, E|
|Calculated MW||29130 Da|
|Immunogen||Recombinant human IGFBP-7|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Insulin-like growth factor-binding protein 7, IBP-7, IGF-binding protein 7, IGFBP-7, IGFBP-rP1, MAC25 protein, PGI2-stimulating factor, Prostacyclin-stimulating factor, Tumor-derived adhesion factor, TAF, IGFBP7, MAC25, PSF|
|Target/Specificity||Rabbit anti Human IGFBP-7 antibody recognizes human IGFBP-7 (insulin-like growth factor binding protein-7), also known as mac25, a 256 amino acid secreted protein and member of a growing family of IGFBPs which regulate the biological activities and distribution of the insulin-like growth factors (IGFs), through binding to IGF-I and IGF-II.IGFBP-7 is widely expressed throughout normal tissues, but is also expressed in many tumour types at an increased or reduced level, and acts as a suppressor of breast and prostate cancer cell lines. IGFBP-7 inhibits IGF-induced differentiation of skeletal muscle (myogenesis) and has implications in bone formation, by its possible affects on the actions of parathyroid hormone (PTH) and cortisol.|
|Preservative & Stabilisers||None present|
|Storage||Store at +4oC or at -20oC if preferred.|
|Precautions||Anti Human IGFBP-7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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