|Immunogen||Keyhole Limpet Haemocyanin conjugated synthetic peptide corresponding to the C-terminal region of rat stargazin.|
|Shelf Life||12 months from date of despatch.|
|Target/Specificity||ABD13302 recognises an epitope within the C-terminal region (CT) of rat stargazin, a 36kDa member of the transmembrane AMPAR regulatory proteins (TARP) family, which plays a vital role in the regulation of the trafficking and localisation/targeting of synaptic AMPA (-amino-3-hydroxy-5-methylisoxazole-4-propionate) receptors (AMPARs).AMPARs are a major group of ionotropic glutamate receptors, highly concentrated at the postsynaptic density (PSD) of excitatory synapses, which require strict regulation for the control of synaptic strength in the brain. Stargazin has been identified as a vital AMPAR-interacting protein which binds to AMPARs via its extracellular domain, whilst interacting with PDZ scaffolding proteins such as PSD-95, via a cytosolic C-terminal PDZ-binding motif.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Rat Stargazin (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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