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Anti Human CD243 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC-P - Anti Human CD243 Antibody  ABD13304
    Staining of formalin fixed, paraffin embedded human adrenal cortex with Rabbit anti Human CD243
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P08183
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 141479 Da
Additional Information
Immunogen Synthetic peptide: cytoplasmic domain of human CD243, conjugated to keyhole limpet hemocyanin.
Shelf Life 18 months from date of despatch.
Gene ID 5243
Other Names Multidrug resistance protein 1,, ATP-binding cassette sub-family B member 1, P-glycoprotein 1, CD243, ABCB1, MDR1, PGY1
Target/Specificity Rabbit anti Human CD243 antibody detects CD243, also known as MDR1 (multi-drug resistance protein 1) and P-glycoprotein. CD243 is a ~170 kDa membrane-associated protein which functions as an ATP-dependent drug efflux pump with broad substrate specificity.CD243 is highly expressed in the kidney, liver, adrenal gland and intestine, suggesting a primary role in the secretion of metabolites into bile, urine and the lumen of the intestinal tract. CD243 also prevents the accumulation of toxic compounds in critical organs such as the brain, gonads, and bone marrow, and also functions in the placenta to protect the foetus.CD243 is rapidly up-regulated by chemotherapeutic drugs and is a well established mediator of multidrug resistance.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human CD243 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13304
(40 western blots)
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