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Anti Human E2F1 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC-P - Anti Human E2F1 Antibody  ABD13311
    Staining of formalin fixed, paraffin embedded human breast carcinoma with Rabbit anti Human E2F1
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q01094
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 46920 Da
Additional Information
Immunogen Synthetic peptide corresponding to amino acid sequence 360-369 of Human E2F-1.
Shelf Life 18 months from date of despatch.
Gene ID 1869
Other Names Transcription factor E2F1, E2F-1, PBR3, Retinoblastoma-associated protein 1, RBAP-1, Retinoblastoma-binding protein 3, RBBP-3, pRB-binding protein E2F-1, E2F1, RBBP3
Target/Specificity Rabbit anti Human E2F1 antibody recognises human E2F1 a ~47 kDa nuclear transcription protein. E2F1 is a transcription activator that binds DNA cooperatively with the differentiation regulated transcription factor proteins (DP). Together they bind to the promoter region of a number of genes whose products are involved in cell cycle regulation or DNA replication. E2F1 also binds to the retinoblastoma protein (RB1), which functions in the control of cell-cycle progression from G1 to S phase. E2F1 can mediate p53-dependent and independent apoptosis. It is a target of the transforming proteins of small DNA tumour viruses and increased expression of this protein has been reported in a variety of cancers.
Preservative & Stabilisers 0.01% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human E2F1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13311
(40 western blots)
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