|Application ||WB, IHC-F|
|Calculated MW||154537 Da|
|Immunogen||A peptide corresponding to amino acids near the carboxy terminus of human ASK1.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Mitogen-activated protein kinase kinase kinase 5, 22.214.171.124, Apoptosis signal-regulating kinase 1, ASK-1, MAPK/ERK kinase kinase 5, MEK kinase 5, MEKK 5, MAP3K5, ASK1, MAPKKK5, MEKK5|
|Target/Specificity||ABD13321 recognises human ASK1 (Apoptosis signal-regulating kinase 1) a 155kDa protein belonging to the protein kinase superfamily.ASK1 is a serine/threonine kinase, also known as MAP kinase kinase kinase (MAPKKK), and plays an important role in the apoptotic response to various stimuli including oxidative stress, cytokines (e.g. TNF) and endoplasmic reticulum stress. Akt in conjunction to Hsp90 phosphorylates ASK1 at Ser83 to inhibit ASK1 induced apoptosis.ASK1 is widely expressed in a variety of human tissues including the heart and pancreas.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human ASK1 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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