|Application ||WB, IHC-P|
|Calculated MW||24822 Da|
|Immunogen||A peptide corresponding to amino acids 215-228 of human DEDAF.|
|Shelf Life||18 months from date of despatch.|
|Other Names||RING1 and YY1-binding protein, Apoptin-associating protein 1, APAP-1, Death effector domain-associated factor, DED-associated factor, YY1 and E4TF1-associated factor 1, RYBP, DEDAF, YEAF1|
|Target/Specificity||Rabbit anti Human DEDAF antibody recognizes human death effector domain associated factor (DEDAF), a 32kDa protein that associates with DED-containing proteins but does not itself contain a DED. DEDAF interacts with the death effector domains of FADD, DEDD and the proforms of caspase-8 and caspase-10. It augments the formation of complexes between CD95, FADD and caspase-8 at the cell membrane and enhances apoptosis. The protein was also independently identified as RING1 and YY1 binding protein (RYBP), which was implicated in the regulation of transcription.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human DEDAF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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