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Anti Human TMS1 (C-Terminal) Antibody

Rabbit Anti-Human Polyclonal Antibody

  • WB - Anti Human TMS1 (C-Terminal) Antibody  ABD13323
    Western blot analysis of whole cell lysate from HL60 promyelocytic leukemia cells probed with Rabbit anti Human TMS1
  • ICC - Anti Human TMS1 (C-Terminal) Antibody  ABD13323
    Immunocytochemical staining of HL60 promyelocytiv leukemia cells with Rabbit anti TMS1
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9ULZ3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 21627 Da
Additional Information
Immunogen A peptide corresponding to aa182-195 of human TMS1.
Shelf Life 18 months from date of despatch.
Gene ID 29108
Other Names Apoptosis-associated speck-like protein containing a CARD, hASC, Caspase recruitment domain-containing protein 5, PYD and CARD domain-containing protein, Target of methylation-induced silencing 1, PYCARD, ASC, CARD5, TMS1
Target/Specificity Rabbit anti Human TMS1 (C-Terminal) antibody recognizes human TMS1, also known as apoptosis-associated speck-like protein containing a CARD (ASC). It was first identified as a cytosolic soluble protein that forms insoluble aggregates and promotes caspase-mediated apoptosis. The proapoptotic activity is mediated predominantly though the activation of caspase 9. It may also be a component of the inflammasome, where it associates with caspase 1, CARD8 and NALP2 to activate proinflammatory caspases. TMS1 is widely expressed in human tissue.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human TMS1 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13323
(40 western blots)
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