|Application ||WB, IHC-P, E|
|Calculated MW||45060 Da|
|Immunogen||Recombinant human PAI-1|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Plasminogen activator inhibitor 1, PAI, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1, SERPINE1, PAI1, PLANH1|
|Target/Specificity||ABD13324 specifically recognises human PAI-1 (plasminogen activator inhibitor-1), otherwise known as SERPINE1, a 45kDa serine protease inhibitor and member of the serpin family, which acts as the primary inhibitor of tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA), and hence fibrinolysis.Increased levels of PAI-1 are associated with diabetes, cardiovascular disease and an increased occurrence of thrombosis in obesity, and can be induced by obesity related factors including insulin, glucose and VLDL (very-low-density lipoprotein).|
|Preservative & Stabilisers||None present|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human PAI-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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