|Application ||WB, IHC-P|
|Calculated MW||85087 Da|
|Immunogen||A peptide corresponding to a 28 amino acid sequence from near the centre of Human BRSK1.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Serine/threonine-protein kinase BRSK1, 22.214.171.124, Brain-selective kinase 1, 126.96.36.199, Brain-specific serine/threonine-protein kinase 1, BR serine/threonine-protein kinase 1, Serine/threonine-protein kinase SAD-B, Synapses of Amphids Defective homolog 1, SAD1 homolog, hSAD1, BRSK1, KIAA1811, SAD1, SADB|
|Target/Specificity||Rabbit anti BRSK1 antibody recognizes human BR serine-threonine kinase 1 (BRSK1), a cytoplasmic and nuclear protein belonging to the protein kinase super family.BRSK1 is a widely expressed protein, with highest levels being detected in the brain and testis. It is essential for the polarization forebrain neurones which results in the distinct properties of axons and dendrites.BRSK1 is involved in the regulation of G2/M arrest and functions as a checkpoint kinase following UV- or methyl methane sulfonate (but not IR-) induced DNA damage. BRSK1 phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitroandin vivo.Multiple isoforms of BRSK1 have been identified.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti BRSK1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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