|Calculated MW||48356 Da|
|Immunogen||A peptide corresponding to 16 amino acids near the carboxy terminus of human IRF8|
|Shelf Life||18 months from date of despatch.|
|Other Names||Interferon regulatory factor 8, IRF-8, Interferon consensus sequence-binding protein, H-ICSBP, ICSBP, IRF8, ICSBP1|
|Target/Specificity||Rabbit anti IRF8 antibody recognizes Interferon regulatory factor 8, (IRF8) also known as Interferon consensus sequence-binding protein (ICSBP). It is part of a transcriptional network that governs B cell lineage specification, commitment and differentiation. It is expressed in T cells, B cells and macrophages. Macrophage, dendritic and B cell development is impaired in IRF deficient mice. IRF8 appears to play a negative regulatory role in IFN induction of genes in most cases.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti IRF8 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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