|Calculated MW||165469 Da|
|Immunogen||Peptide from the N-terminus of the NR2A subunit of rat NMDA receptor.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Glutamate receptor ionotropic, NMDA 2A, GluN2A, Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, Grin2a|
|Target/Specificity||ABD13345 recognises the NR2A subunit of the NMDA (N-methyl-D-aspartate) receptor. Receptors for NMDA belong to a group of ionotropic glutamate receptors which play a key role in the mediation of glutamate neurotransmission within the mammalian central nervous system (CNS), including involvement in memory and learning processes. Several antagonists and agonists of NMDA receptors (NMDAR) have been identified. Properties of NMDAR include modulation by glycine, inhibition by Zn2+, voltage-dependent Mg2+ blockade and high Ca2+permeability.The involvement of NMDAR in the CNS has become a focus area for neurodegenerative diseases such as Alzheimer’s disease and also epilepsy and ischemic neuronal cell death.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Rat NMDA Receptor NR2A (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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