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Anti Human LRP6 Antibody

Goat Anti-Human Polyclonal Antibody

  • IHC-P - Anti Human LRP6 Antibody  ABD13358
    Staining of formalin fixed, paraffin embedded huan liver with Rabbit anti Human LRP6
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75581
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 180429 Da
Additional Information
Immunogen Synthetic peptide sequence (C)MTSVATAKGYTSDL corresponding to an internal region of human LRP6.
Shelf Life 18 months from date of despatch.
Gene ID 4040
Other Names Low-density lipoprotein receptor-related protein 6, LRP-6, LRP6
Target/Specificity Goat anti Human LRP6 antibody recognizes human Low-density lipoprotein receptor-related protein 6 (LRP-6). LRP6 is a widely expressed 1594 amino acid ~:200 kDa single pass type I endoplasmic reticular transmembrane glycoprotein. LRP6 is released from the endoplasmic reticulum of palmitoylation.LRP6 is involved with Wnt Frizzled and LRP5 in the formation of signalosomes, inducing beta catenin signaling (Bilicet al.2007). Mutations in the LRP6 gene can lead to development of Coronary artery disease, autosomal dominant, 2 (ADCAD2) a disease characterised by reduced or absent blood flow in one or more arteries supplying the heart which can in some cases lead to acute myocardial infarction (Maniet al.2007).
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human LRP6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13358
(40 western blots)
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