|Application ||WB, E|
|Calculated MW||48949 Da|
|Immunogen||Synthetic peptide sequence C-RTQTTSAKQEKAP from the C-Terminal region of EXOSC9 (NP_001029366.1; NP_005024.2).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Exosome complex component RRP45, Autoantigen PM/Scl 1, Exosome component 9, P75 polymyositis-scleroderma overlap syndrome-associated autoantigen, Polymyositis/scleroderma autoantigen 1, Polymyositis/scleroderma autoantigen 75 kDa, PM/Scl-75, EXOSC9, PMSCL1|
|Target/Specificity||ABD13365 specifically recognises an epitope within the C-Terminal (CT) region of human Exosome component 9 (EXOSC9), otherwise known as PMSCL1.EXOSC9 is a member of the RNase PH family, and component of the exosome 3'->5' exoribonuclease (PM/Scl) complex, which exhibits exonuclease activity, and is involved in the degradation of unstable RNA, and the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA . EXOSC9 has been identified as an autoantigen in patients with the complex auto immune disease scleromyositis.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human Exosome Component 9 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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