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Anti Human CD54 Antibody

Rabbit Anti-Human Polyclonal Antibody

     
  • IHC-P - Anti Human CD54 Antibody  ABD13372
    Paraffin embedded, formalin fixed human breast invasive ductal adenocarcinoma stained with Rabbit anti human CD54 following enzyme mediated antigen retrieval using proteinase K
  • IHC-P - Anti Human CD54 Antibody  ABD13372
    Paraffin embedded, formalin fixed human breast invasive ductal adenocarcinoma stained with Rabbit anti human CD54 following enzyme mediated antigen retrieval using proteinase K
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P05362
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 57825 Da
Additional Information
Immunogen Recombinant human CD54.
Shelf Life 18 months from the date of despatch
Gene ID 3383
Other Names Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor, CD54, ICAM1
Target/Specificity Rabbit anti Human CD54 antibody recognizes human CD54, otherwise known as Intercellular adhesion molecule 1 or ICAM-1. CD54 is a 532 amino acid single pass type I membrane glycoprotein containing five Ig-like C2-type domains. CD54 is widely expressed and acts as a ligand for the leukocyte integrin LFA-1 (CD11a/CD18) and Mac-1 integrins, it is the major receptor for human rhinovirus(Stauntonet al.1989).CD54 is highly expressed on activated endothelial cells (Favoloro 1993) and plays a role in transendothelial cell migration to sites of acute inflammation, functioning primarily as an adhesion molecule between endothelial cells and leucocytes, following injury or stress (Manes and Pober 2011). Levels of soluble CD54 in serum (Matalliotakiset al.2001) or urine (Kimet al.2006), can be potentially used as an indication of infection, inflammation and certain tumour, and as a target for immunosuppression in transplantation.
Preservative & Stabilisers None present
Storage Prior to reconstitution store at +4℃.After reconstitution store at -20℃.
PrecautionsAnti Human CD54 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13372
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