|Application ||IHC-F, FC, E, Func|
|Calculated MW||58844 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Shelf Life||18 months from date of despatch.|
|Other Names||Intercellular adhesion molecule 1, ICAM-1, MALA-2, MyD10, CD54, Icam1, Icam-1|
|Target/Specificity||Hamster anti Mouse CD54 antibody, clone 3E2B recognizes murine Intercellular adhesion molecule 1, also known as ICAM-1, CD54, MALA-2 or MyD10. CD54 is a 537 amino acid ~89kDa single pass type I transmembrane glycoprotein bearing five Ig-like C2 type domains. Two isoforms, differing at the N-terminal signal peptide sequence and flanking end terminal domain of the processed molecule are generrated by alternative splicing(UniProt P13577) . CD45 is a counter-receptor for LFA-1(Diamondet al.1990)Murine CD54 is expressed at low levels on T-cells, B-cells, monocytes and endothelial cells but can be induced strongly by a number of stimuli, including UV radiation (Tang and Udey 1991).|
|Preservative & Stabilisers||None present|
|Storage||Store at -20℃ only.|
|Precautions||Anti Mouse CD54 Antibody, clone 3E2B is for research use only and not for use in diagnostic or therapeutic procedures.|
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