|Application ||WB, FC, IP|
|Calculated MW||85026 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Membrane glycoproteins of cytotoxic T-cells.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150, 95 subunit beta, Complement receptor C3 subunit beta, CD18, Itgb2|
|Target/Specificity||Rat anti Mouse CD18 antibody, clone M18/2 recognizes the murine beta 2 integrin (CD18). CD18 is a 95 kDa cell surface glycoprotein that forms heterodimers with the integrin subunit alpha L (CD11a), alpha M (CD11b) or alpha X (CD11c) to produce integrins CD11a/CD18, CD11b/CD18 and CD11c/CD18 respectively.CD18 is expressed by all leucocytes and plays an important role in adhesion and signalling in the haematopoietic system.Rat anti Mouse CD18 antibody, clone M18/2 has been reported to both inhibit and enhance certain functions of CD18 (Sanchez-Madridet al.1983andDriessenset al.1996).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Mouse CD18 Antibody, clone M18/2 is for research use only and not for use in diagnostic or therapeutic procedures.|
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