|Application ||WB, IF, FC, E|
|Calculated MW||40524 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Synthetic phospho peptide corresponding to the C-Terminal region of human CD195 conjugated to BSA.|
|Shelf Life||18 months from date of despatch.|
|Other Names||C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5, CHEMR13, HIV-1 fusion coreceptor, CD195, CCR5, CMKBR5|
|Target/Specificity||Mouse anti Human CD195 (pSer349) antibody, clone E11/19 recognizes human CD195 when phosphorylated at Ser 349 (Pollok-Kopp et al. 2003). CD195 is a cell surface antigen of approximately 40 kDa, also known as CCR5. Human CD195 is a member of the G protein coupled superfamily of receptors, which acts as a receptor for a number of chemokines including RANTES and also serves as a co-receptor for the entry of HIV into cells. It plays a key role in regulating the activation and migration of leukocytes. CD195 is expressed by a subset of T lymphocytes and by monocytes.Following ligand stimulation, CD195 is rapidly phosphorylated within the C-terminal domain. Mouse anti Human CD195 (pSer349) antibody, clone E11/19 recognises a band of ~40 kDa on western blots of RBL-CCR5 cell lysates.|
|Preservative & Stabilisers||0.09%Sodium Azide|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human CD195 (pSer349) Antibody, clone E11/19 is for research use only and not for use in diagnostic or therapeutic procedures.|
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