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Anti Mouse CD121a Antibody, clone JAMA-147

Hamster Anti-Mouse Monoclonal Antibody

  • FC - Anti Mouse CD121a Antibody, clone JAMA-147  ABD13414
    Staining of NIH-3T3 cells with Hamster anti Mouse CD121a: Alexa Fluor® 647
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P13504
Reactivity Mouse
Host Hamster
Clonality Monoclonal
Isotype IgG
Clone Names JAMA-147
Calculated MW 66698 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Extracellular domain of murine IL-1R.
Shelf Life 18 months from date of despatch.
Gene ID 16177
Other Names Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, IL-1R-alpha, Interleukin-1 receptor type I, p80, CD121a, Interleukin-1 receptor type 1, membrane form, mIL-1R1, mIL-1RI, Interleukin-1 receptor type 1, soluble form, sIL-1R1, sIL-1RI, Il1r1, Il-1r1, Il1ra
Target/Specificity Hamster anti Mouse CD121a monoclonal antibody, clone JAMA-147 recognizes murine CD121a, the ~80 kDa type I interleukin-1 receptor. CD121a is a single pass type I membrane glycoprotein, weakly expressed on most cells and tissues including T lymphocytes, thymocytes, epithelial cells and dendritic cells, with stronger expression reported on fibroblasts.The ligands for CD121a are the interleukin-1 (IL-1) family members; IL-1 alpha; IL-1 beta and IL-1 receptor antagonist. IL-1 is a mediator of inflammation and can elicit a variety of other biological responses through binding to CD121a.Hamster anti mouse CD121 antibody, clone JAMA-147 has been reported to block IL-1 dependent cellular responses (Rogerset al.1992).
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Mouse CD121a Antibody, clone JAMA-147 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13414
(40 western blots)
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