|Application ||WB, IF, FC, Func|
|Calculated MW||34494 Da|
|Other Species||American Bison|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Fusion protein consisting of the extracellular region of bovine CD335.|
|Shelf Life||18 months from the date of despatch|
|Other Names||Natural cytotoxicity triggering receptor 1, Natural killer cell p46-related protein, NK-p46, NKp46, CD335, NCR1|
|Target/Specificity||Mouse anti Bovine CD335 antibody, clone AKS1 recognizes bovine CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is expressed by human natural killer cells (Sivoriet al.1997). The bovine homologue is expressed on bovine NK cells (Storsetet al.2004) and no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes.Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells (Storsetet al.2004).|
|Preservative & Stabilisers||None present|
|Storage||Store at -20℃ only.|
|Precautions||Anti Bovine CD335 Antibody, clone AKS1 is for research use only and not for use in diagnostic or therapeutic procedures.|
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