|Calculated MW||39023 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||RBL-2H3 transfected cells expressing murine C5aR.|
|Shelf Life||18 months from date of despatch.|
|Other Names||C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, CD88, C5ar1, C5ar, C5r1|
|Target/Specificity||Rat anti Mouse CD88 monoclonal antibody recognizes murine CD88, also known as C5a anaphylatoxin chemotactic receptor 1 (C5aR). a member of the G-protein coupled receptor 1 family. CD88 is a ~45kDa multi pass membrane protein and functions as a receptor for the complement component C5a, a potent proinflammatory molecule and a chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes. Clone 20/70 has been reported to block the binding of the C5a to murine CD88, (Soruriet al.2003).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Mouse CD88 Antibody, clone 20/70 is for research use only and not for use in diagnostic or therapeutic procedures.|
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