|Application ||WB, FC|
|Calculated MW||69872 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Immunogen||Bacterially expressed fusion protein corresponding to the C-terminal region of human Zap-70.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Tyrosine-protein kinase ZAP-70, 188.8.131.52, 70 kDa zeta-chain associated protein, Syk-related tyrosine kinase, ZAP70, SRK|
|Target/Specificity||ABD13437 recognises human ZAP-70, a 70kD tyrosine protein kinase which associates with the T-cell receptor (TCR) zeta chain and undergoes phosphorylation following TCR stimulation. ZAP-70 is primarily expressed in T lymphocytes and natural killer cells, where it plays a key role in T-cell receptor (TCR) signalling. Recent studies suggest that ZAP-70 is also expressed in a population of normal immature B-cells and in B-cells from a sub-set of patients with chronic lymphocytic leukaemia.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human ZAP 70 Antibody, clone ZAP-03 is for research use only and not for use in diagnostic or therapeutic procedures.|
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