Anti Human Complement Factor BB Neoantigen Antibody, clone 032B-22.1.X
Mouse Anti-Human Monoclonal Antibody
|Application ||WB, FC, E|
|Calculated MW||85533 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Immunogen||Purified Human factor B|
|Shelf Life||18 months from date of despatch.|
|Other Names||Complement factor B, 220.127.116.11, C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B, Complement factor B Ba fragment, Complement factor B Bb fragment, CFB, BF, BFD|
|Target/Specificity||Mouse anti human complement factor Bb neoantigen monoclonal antibody, clone 032B-22.1.X recognizes a neoantigen of the Bb fragment of human complement factor B. Factor B is present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit) leaving the 63 kDa Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human Complement Factor BB Neoantigen Antibody, clone 032B-22.1.X is for research use only and not for use in diagnostic or therapeutic procedures.|
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