|Application ||IF, FC|
|Calculated MW||253912 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||ABCA1 transfected HeLa cells.|
|Shelf Life||18 months from date of despatch.|
|Other Names||ATP-binding cassette sub-family A member 1, ATP-binding cassette transporter 1, ABC-1, ATP-binding cassette 1, Abca1, Abc1|
|Target/Specificity||Rat anti Mouse ABCA1 antibody, clone 5A1-1422 recognizes murine adenosine triphosphate (ATP) Binding cassette transporter 1 (ABCA1). The ABC transporters are a large family of conserved proteins that transport a wide variety of molecules across cellular membranes. ABCA1 is a member of the ABC-A sub-family, which acts as a lipid translocator. The molecule was originally identified as a scavenger receptor on macrophages and research shows that ABCA1 also plays a major role in cholesterol metabolism. ABCA1 may play an important role in protecting against cardiovascular disease.Mutations in ABCA1 gene have been associated with Tangiers disease, a genetic disorder of lipid metabolism, and familial high density lipoprotein (HDL) deficiency.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Mouse ABCA1 Antibody, clone 5A1-1422 is for research use only and not for use in diagnostic or therapeutic procedures.|
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