|Application ||WB, E|
|Calculated MW||23171 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Shelf Life||18 months from date of despatch.|
|Other Names||Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1, TIMP1, CLGI, TIMP|
|Target/Specificity||Mouse anti Human TIMP-1 antibody, clone T2 recognizes human Metalloproteinase inhibitor 1, also known as TIMP-1, Erythroid-potentiating activity, Fibroblast collagenase inhibitor or Tissue inhibitor of metalloproteinases 1. TIMP-1 is a 207 amino acid ~28 kDa secreted metalloproteinase inhibitor. reacting with both the reduced and non-reduced forms of TIMP-1 (UniProt: P101033).TIMP-1 is expressed by a wide range of cells including microvascular endothelial cells, smooth muscle cells, mesangial cells and some fibroblasts. TIMP-1 inhibits matrix metalloproteinase activity by forming complexes via reversible non covalent binding. It is reported to be involved in the control of angiogenesis and tumour growth. Mouse anti Human TIMP-1 antibody, clone T2 has been shown to inhibit biological activity (Koikeet al.2002).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human TIMP-1 Antibody, clone T2 is for research use only and not for use in diagnostic or therapeutic procedures.|
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