|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatantPurified IgG prepared by affinity chromatography on Protein A from tissue culture supernatantPurified IgG prepared by affinity chromatography on Protein G from ti|
|Immunogen||Purified Equine Ig.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti Horse Pan B-Cells, clone CVS36 is a monoclonal antibody directed against equine Ig light chains. Characterization studies demonstrated that clone CVS36 bound 100% of CD5-ve peripheral blood lymphocytes and recognized all equine B-cells (Lunnet al.1998) As the antigen recognized by clone CVS36 appears to be present on the surface of all equine B-cells it is therefore is a reagent that can be used as a pan B-cell marker for domestic horses (Breathnachet al.2005).Specific anti equine reagents have yet to be fully characterized for the typically recognized B-cell makers such as CD19, CD20, CD21, CD22 and CD79. While testing has demonstrated the cross reactivity of some monoclonal B-cell markers raised against other species with equine B cells, such as the Mouse anti Human CD79a antibody, (clone HM57), an overview of which may be found in the report of the second equine leucocyte antigen workshop (Lunnet al.1998).With specificity for equine Ig light chains, clone CVS36 may be used to detect all equine immunoglobulin classes and subclasses in ELISA applications (Lunnet al.1998).|
|Preservative & Stabilisers||0.09% Sodium Azide, 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Horse Pan B-Cells Antibody, clone CVS36 is for research use only and not for use in diagnostic or therapeutic procedures.|
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