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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti Human IRF5 Antibody, clone 10T1    

Anti Human IRF5 Antibody, clone 10T1

Mouse Anti-Human Monoclonal Antibody

  • WB - Anti Human IRF5 Antibody, clone 10T1  ABD13513
    Western blot analysis of IRF5 expression in a range of cell lines using Mouse anti Human IRF5
  • IHC-P - Anti Human IRF5 Antibody, clone 10T1  ABD13513
    Formalin fixed, paraffin embedded normal colon and colon adenocarcinoma stained with Mouse anti Human IRF5 following heat mediated antigen retrieval using 0.1M citrate buffer (pH6.0)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13568
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 10T1
Calculated MW 56044 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Histidine-tagged recombinant peptide corresponding to amino acids 176-240 of human IRF5, purified from E. coli.
Shelf Life 18 months from date of despatch.
Gene ID 3663
Other Names Interferon regulatory factor 5, IRF-5, IRF5
Target/Specificity Mouse anti Human IRF5, clone 10T1 recognises human interferon regulatory factor 5 (IRF5), a 58kDa member of the IRF family which acts as a key regulator of interferon gene transcription, and is expressed in B cells and dendritic cells, and is inducible by type I interferon (IFN) in most lymphoid cells.The role of IRF3 and IRF7 as transcriptional mediators of virus- and IFN-induced signaling pathways is well documented. Studies have shown that IRF5 can also regulate IFN gene transcription, but appears to be more restricted in its cellular expression and range of viral stimuli, and has the ability to induce a wide range of chemokines involved in T-lymphocyte recruitment, including RANTES, MCP-1 and IP-10 (Barneset al.2002).
Preservative & Stabilisers 0.1% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human IRF5 Antibody, clone 10T1 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13513
(40 western blots)
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