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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti Human TLR7 Antibody, clone 4F4    

Anti Human TLR7 Antibody, clone 4F4

Mouse Anti-Human Monoclonal Antibody

  • WB - Anti Human TLR7 Antibody, clone 4F4  ABD13514
    Western blot analysis of TLR7 expression against recombinant TLR7 using Mouse anti Human TLR7
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NYK1
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 4F4
Calculated MW 120922 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Recombinant human TLR7 (amino acids 451-500) purified from Escherichia coli.
Shelf Life 18 months from date of despatch.
Gene ID 51284
Other Names Toll-like receptor 7, TLR7
Target/Specificity Mouse anti Human TLR7, clone 4F4 recognizes human TLR7 (toll-like receptor 7), a 121 kDa type I transmembrane protein belonging to the toll-like receptor (TLR) family. TLR7is predominantly expressed in the spleen, lung and placenta (Chuanget al.2000).TLRs are highly conserved proteins which play a key role in activation of innate immunity, through the recognition of distinct molecular patterns expressed by infectious agents. TLR7 recognizes and interacts with single-stranded RNA (ssRNA) derived from viruses such as influenza , HIV-1 (human immunodeficiency virus type I) and Sendai, and some siRNAs, resulting in the activation of the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway, and the production of proinflammatory signaling molecules (Dieboldet al.2004)
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human TLR7 Antibody, clone 4F4 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13514
(40 western blots)
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