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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti Human CD300a Antibody, clone MEM-260    

Anti Human CD300a Antibody, clone MEM-260

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UGN4
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names MEM-260
Calculated MW 33201 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.
Immunogen Human HPB acute lymphoid leukaemia cell line.
Shelf Life 18 months from date of despatch.
Gene ID 11314
Other Names CMRF35-like molecule 8, CLM-8, CD300 antigen-like family member A, CMRF-35-H9, CMRF35-H9, CMRF35-H, IRC1/IRC2, Immunoglobulin superfamily member 12, IgSF12, Inhibitory receptor protein 60, IRp60, NK inhibitory receptor, CD300a, CD300A, CMRF35H, IGSF12
Target/Specificity Mouse anti Human CD300a antibody, clone MEM-260 recognizes human CD300a, otherwise known as IRp60 or inhibitory receptor protein 60, CD300a is a ~60 kDa transmembrane glycoprotein expressed by natural killer cells (NK), T and B cell subsets, monocytes, neutrophils, macrophages, granulocytes, dendritic cells (DC) and mast cells.Cross-linking of CD300a on NK results in a down-regulation of their cytolytic activity, whilst cross-linking of CD300a on mast cells, inhibits IgE-induced degranulation and SCF-mediated survival. Furthermore, cross-linking of CD300a on the surface of eosinophils has been shown to significantly inhibit their survival, chemotaxis and activation in response to certain inflammatory cytokines, whilst eosinophil-derived MBP (major basic protein) and EDN (neurotoxin), can down-regulate CD300a expression on mast cells in vitro(
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human CD300a Antibody, clone MEM-260 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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$ 320.00
Cat# ABD13515
1 Formats Available
Availability: 5-7days
Bulk Size
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