|Calculated MW||39204 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Recombinant mouse CD14.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Cd14|
|Target/Specificity||Mouse anti Mouse CD14 antibody, clone biG53 recognizes mouse CD14, a ~55 kDa a glycophosphoinositol-linked cell surface protein that also exists in a soluble form. Expression of CD14 is restricted to the myeloid lineage and is predominantly expressed on peripheral blood monocytes, weakly expressed on granulocytes and absent on myeloid progenitors. The CD14 molecule acts as a pattern recognition receptor, which binds lipopolysaccharide (LPS) and other microbial products such as lipoteichoic acid, lipoproteins and peptidoglycan. Binding of LPS to CD14 mediates the innate immune response to LPS and requires the Toll-like receptor-4 (TLR4)/MD-2 complex for effective signalling.Mouse anti Mouse CD14 antibody, clone biG53 inhibits the binding of CD14.|
|Preservative & Stabilisers||0.09% Sodium Azide, 1% Bovine Serum Albumin, 5% Sucrose|
|Storage||Store at +4℃.DO NOT FREEZE.|
|Precautions||Anti Mouse CD14 Antibody, clone biG53 is for research use only and not for use in diagnostic or therapeutic procedures.|
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