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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti Human Troponin Complex (Cardiac) Antibody, clone 20C6    

Anti Human Troponin Complex (Cardiac) Antibody, clone 20C6

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P45379
Other Accession P63316, P19429
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Clone Names 20C6
Calculated MW 35924 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Immunogen Human native troponin complex
Shelf Life 18 months from date of despatch.
Gene ID 7139
Other Names Troponin T, cardiac muscle, TnTc, Cardiac muscle troponin T, cTnT, TNNT2
Target/Specificity Mouse anti Human Troponin Complex (Cardiac) antibody, clone 20C6 recognizes human troponin, a complex of three proteins integral to muscle contraction. The three-unit troponin complex (Troponin I, T and C), bound to tropomyosin, is located on the actin filament of skeletal and cardiac muscle. Troponin T binds to tropomyosin to form the troponin-tropomyosin complex. Troponin C binds calcium ions to produce a conformational change in Troponin I. Troponin I binds to the actin in thin myofilaments to hold the troponin-tropomyosin complex in place. When calcium binds to troponin, a conformation change is forced in troponin and tropomyosin, moving both proteins away from the myosin binding sites on the actin filaments. Thus, myosin can bind to actin and muscle contraction occurs.Mouse anti Human Troponin Complex (Cardiac) antibody, clone 20C6 recognizes the native troponin complex. It does not cross-react with any of the individual components Troponin I, T or C.
Preservative & Stabilisers 0.09%Sodium Azide
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human Troponin Complex (Cardiac) Antibody, clone 20C6 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13524
(40 western blots)
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