|Other Accession||P63316, P19429|
|Calculated MW||35924 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Immunogen||Human native troponin complex|
|Shelf Life||18 months from date of despatch.|
|Other Names||Troponin T, cardiac muscle, TnTc, Cardiac muscle troponin T, cTnT, TNNT2|
|Target/Specificity||Mouse anti Human Troponin Complex (Cardiac) antibody, clone 20C6 recognizes human troponin, a complex of three proteins integral to muscle contraction. The three-unit troponin complex (Troponin I, T and C), bound to tropomyosin, is located on the actin filament of skeletal and cardiac muscle. Troponin T binds to tropomyosin to form the troponin-tropomyosin complex. Troponin C binds calcium ions to produce a conformational change in Troponin I. Troponin I binds to the actin in thin myofilaments to hold the troponin-tropomyosin complex in place. When calcium binds to troponin, a conformation change is forced in troponin and tropomyosin, moving both proteins away from the myosin binding sites on the actin filaments. Thus, myosin can bind to actin and muscle contraction occurs.Mouse anti Human Troponin Complex (Cardiac) antibody, clone 20C6 recognizes the native troponin complex. It does not cross-react with any of the individual components Troponin I, T or C.|
|Preservative & Stabilisers||0.09%Sodium Azide|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human Troponin Complex (Cardiac) Antibody, clone 20C6 is for research use only and not for use in diagnostic or therapeutic procedures.|
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