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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti Human Troponin C Antibody, clone 1A2    

Anti Human Troponin C Antibody, clone 1A2

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P63316
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Clone Names 1A2
Calculated MW 18403 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Immunogen Human slow skeletal troponin C
Shelf Life 18 months from date of despatch.
Gene ID 7134
Other Names Troponin C, slow skeletal and cardiac muscles, TN-C, TNNC1, TNNC
Target/Specificity Mouse anti Human Troponin C antibody, clone 1A2 recognizes human Troponin C, an 18kDa subunit of the Troponin complex found on actin filaments in muscle tissue. Troponin C (TnC) is responsible for binding calcium ions. In the absence of calcium, TnC has an inhibitory action on the actin filaments. When calcium binds to TnC, a conformational change takes place in Troponin I, which in turn causes a change in another associated protein, tropomyosin. Troponin and tropomyosin is repositioned away from the actin filaments, leaving the myosin binding sites available for cross-bridges to form and muscle contraction to occur. Mouse anti Human Troponin C antibody, clone 1A2 recognizes free cardiac Troponin C and TnC in binary complex with cardiac Troponin I. The antibody does not recognize free cardiac Troponin I or cardiac Troponin T.
Preservative & Stabilisers 0.09%Sodium Azide
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human Troponin C Antibody, clone 1A2 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13525
(40 western blots)
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