|Application ||IHC-F, FC, Func|
|Calculated MW||127829 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Immunogen||Recombinant human CD11c.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150, 95 alpha chain, Leukocyte adhesion receptor p150, 95, CD11c, ITGAX, CD11C|
|Target/Specificity||Mouse anti Human CD11c antibody, clone CBR-p150/4G1 specifically recognizes human CD11c, otherwise known as integrin alpha X chain and leukocyte adhesion receptor p150,95, a ~150 kDa type I transmembrane protein and member of the integrin alpha chain family, expressed by monocytes, macrophages, granulocytes and NK cells, and is a marker for hairy cell leukaemia cells. CD11c combines with the CD18 beta chain (ITGB2) to form the leukocyte specific integrin CR4, acts as a mediator of leukocyte adherence to endothelium, and binds to the ligands CD54 (ICAM1), iC3b and fibrinogen. Mouse anti Human CD11c antibody, clone CBR-p150/4G1 inhibits the binding of CD11c to endothelial cells. Mouse anti Human CD11c antibody, clone CBR-p150/4G1 does not recognize CD11a, CD11b or CD18.|
|Preservative & Stabilisers||None present|
|Storage||Store at -20℃ only.|
|Precautions||Anti Human CD11c Antibody, clone CBR-p150/4G1 is for research use only and not for use in diagnostic or therapeutic procedures.|
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