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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti Human CD120a Antibody, clone H398    

Anti Human CD120a Antibody, clone H398

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-F, FC, IP, Func
Primary Accession P19438
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Clone Names H398
Calculated MW 50495 Da
Additional Information
Immunogen Recombinant CD120a.
Shelf Life 18 months from date of despatch.
Gene ID 7132
Other Names Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, TNF-R1, Tumor necrosis factor receptor type I, TNF-RI, TNFR-I, p55, p60, CD120a, Tumor necrosis factor receptor superfamily member 1A, membrane form, Tumor necrosis factor-binding protein 1, TBPI, TNFRSF1A, TNFAR, TNFR1
Target/Specificity Mouse anti Human CD120a antibody, clone H398 recognizes both the 60 kDa cell surface and soluble fragment of human CD120a, otherwise known as TNF receptor type I (TNFR1/sTNFR1), a ubiquitously expressed transmembrane glycoprotein and member of the tumour necrosis factor receptor (TNFR) superfamily, which plays a key role in regulating the inflammatory response, acting as a receptor for tumour necrosis factor alpha (TNF-alpha) and lymphotoxin-alpha (TNF-beta). CD120a also plays a role in apoptosis, cytokine induction, cell differentiation, tumour necrosis and early stages of graft-versus-host disease, and its soluble form sTNFR1, acts as an inhibitor of TNF-alpha induced responses by acting as a decoy receptor. Mouse anti Human CD120a antibody, clone H398 completely inhibits functional activity via CD120a by inhibiting receptor signalling, but does not always inhibit ligand binding of TNF. Mouse anti Human CD120a antibody, clone H398 has been used successfully in functional studies on U937, K562, Colo 205, YT, MCF-7, HeLa and L929 cells (Thomaet al.1990)..
Preservative & Stabilisers None present
Storage Store at -20℃ only.
PrecautionsAnti Human CD120a Antibody, clone H398 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13530
(40 western blots)
Availability: Inquire
Bulk Size
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