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>   home   >   Products   >   Primary Antibodies   >   Anti-CDK6 Antibody (Monoclonal, DCS-90)   

Anti-CDK6 Antibody (Monoclonal, DCS-90)

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, ICC
Primary Accession F1MA87
Host Mouse
Isotype Mouse IgG1
Reactivity Human, Mouse, Rat
Clonality Monoclonal
Format Lyophilized
Description Mouse IgG monoclonal antibody for CDK6, cyclin-dependent kinase 6 (CDK6) detection. Tested with WB, ICC in Human;mouse;rat. No cross reactivity with other proteins.
Reconstitution Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Additional Information
Calculated MW 36952 MW KDa
Application Details Immunocytochemistry , 1 µg/ml, Human, mouse, rat, -
Western blot, 0.5-1 µg/ml, Human, mouse, rat
Subcellular Localization CDK6: Cytoplasm. Nucleus. Cell projection, ruffle.Cytoplasm, cytoskeleton, microtubule organizing center, centrosome|Cdk6: Cytoplasm
Tissue Specificity CDK6: Expressed ubiquitously. Accumulates insquamous cell carcinomas, proliferating hematopoietic progenitorcells, beta-cells of pancreatic islets of Langerhans, andneuroblastomas. Reduced levels in differentiating cells.
Protein Name Cyclin-dependent kinase 6
Contents Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Clone Names DCS-90
Immunogen Recombinant human Cdk6 protein.
Purification Ascites
Cross Reactivity No cross reactivity with other proteins
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Sequence Similarities Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein Information
Citations (0)

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Background

The cyclin-dependent protein kinases(CDKs) regulate major cell cycle transitions in eukaryotic cells. Cyclin-dependent kinase-6(CDK6) is the earliest inducible member of the CDK family in human T lymphocytes, involved in growth factor stimulation and cell cycle progression. Germline mutations in CDK6 do not make a significant contribution to melanoma predisposition. CDK6 gene is mapped at 7q21-q22.

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$ 240.00
Cat# ABO10416
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