Anti-MAP2 Antibody (Monoclonal, HM-2)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | P15146 |
Host | Mouse |
Isotype | Mouse IgG1 |
Reactivity | Human, Mouse, Rat |
Clonality | Monoclonal |
Format | Lyophilized |
Description | Mouse IgG monoclonal antibody for MAP2, microtubule-associated protein 2 (MAP2) detection. Tested with WB, IHC-P in Human;mouse;rat. No cross reactivity with other proteins. |
Reconstitution | Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
Gene ID | 25595 |
---|---|
Other Names | Microtubule-associated protein 2, MAP-2, Map2, Mtap2 |
Calculated MW | 202411 MW KDa |
Application Details | Immunohistochemistry(Paraffin-embedded Section), 1-2 µg/ml, Human, mouse, rat, By Heat Western blot, 0.5-2 µg/ml, Human, mouse, rat |
Subcellular Localization | Cytoplasm, cytoskeleton . |
Protein Name | Microtubule-associated protein 2 |
Contents | Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. |
Clone Names | HM-2 |
Immunogen | Rat brain microtubule-associated proteins(MAPs). |
Purification | Ascites |
Cross Reactivity | No cross reactivity with other proteins |
Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
Sequence Similarities | Contains 3 Tau/MAP repeats. |
Name | Map2 |
---|---|
Synonyms | Mtap2 |
Function | The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. |
Cellular Location | Cytoplasm, cytoskeleton. Cell projection, dendrite {ECO:0000250|UniProtKB:P20357} |
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Provided below are standard protocols that you may find useful for product applications.
Background
MAP2, a 280-kD protein, is highly concentrated in neuronal somata and dendrites. Microtubule-associated protein 2(MAP2)is a neurosteroid receptor. MAP2 gene contains 19 exons, and located in segment 2q34-q35. The transgenic MAP2c was present in dendrites but not in axons but transgenic MAP2c messenger RNA was limited to cell bodies.
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