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Anti-CD56/NCAM-1 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, ICC |
|---|---|
| Primary Accession | P13596 |
| Host | Mouse |
| Isotype | Mouse IgG1 |
| Reactivity | Human, Mouse, Rat |
| Clonality | Monoclonal |
| Format | Lyophilized |
| Description | Mouse IgG monoclonal antibody for NCAM, neural cell adhesion molecule 1 (NCAM1) detection. Tested with WB, ICC in Human;mouse;rat. No cross reactivity with other proteins. |
| Reconstitution | Add 1ml of PBS buffer will yield a concentration of 100ug/ml. |
| Gene ID | 24586 |
|---|---|
| Other Names | Neural cell adhesion molecule 1, N-CAM-1, NCAM-1, CD56, Ncam1, Ncam |
| Calculated MW | 94658 MW KDa |
| Application Details | Immunocytochemistry , 1 µg/ml, Human, mouse, rat, - Western blot, 4 µg/ml, Human, mouse, rat |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. |
| Protein Name | Neural cell adhesion molecule 1 |
| Contents | Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. |
| Clone Names | NCAM-0B11 |
| Immunogen | Growth cone enriched plasma membrane fraction from E17 rat forebrain. |
| Purification | Ascites |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
| Sequence Similarities | Contains 2 fibronectin type-III domains. |
| Name | Ncam1 {ECO:0000312|RGD:67378} |
|---|---|
| Synonyms | Ncam |
| Function | This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The neural cell adhesion molecule appears on early embryonic cells and is important in the formation of cell collectives and their boundaries at sites of morphogenesis. Later in development it is found on various differentiated tissues and is a major CAM mediating adhesion among neurons and between neurons and muscle. NCAM shares many features with immunoglobulins and is considered a member of the immunoglobulin superfamily NCAM gene is mapped to 11q23.1.
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