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Anti-Tryptophan Hydroxylase Antibody (Monoclonal, WH-3)

     
  • WB - Anti-Tryptophan Hydroxylase Antibody (Monoclonal, WH-3) ABO10483
    Anti-Tryptophan Hydroxylase antibody (monoclonal), ABO10483, Western blottingLane 1: Rat Brain Tissue LysateLane 2: Rat Brain Tissue Lysate
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q8CGU9
Host Mouse
Isotype Mouse IgG3
Reactivity Human, Rat
Clonality Monoclonal
Format Lyophilized
Description Mouse IgG monoclonal antibody for Tryptophan Hydroxylase, tryptophan hydroxylase 1; tryptophan hydroxylase 2 (TPH1; TPH2) detection. Tested with WB in Human;rat;rabbit. No cross reactivity with other proteins.
Reconstitution Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Additional Information
Gene ID 317675
Other Names Tryptophan 5-hydroxylase 2, 1.14.16.4, Neuronal tryptophan hydroxylase, Tryptophan 5-monooxygenase 2, Tph2, Ntph
Calculated MW 55621 MW KDa
Application Details Western blot, 0.5-1 µg/ml, Human, rat, rabbit
Tissue Specificity TPH1: Isoform 2 seems to be less widely expressedthan isoform 1.
Protein Name Tryptophan 5-hydroxylase 1; Tryptophan 5-hydroxylase 2
Contents Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Clone Names WH-3
Immunogen Recombinant rabbit tryptophan hydroxylase.
Purification Ascites
Cross Reactivity No cross reactivity with other proteins
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Sequence Similarities Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Protein Information
Name Tph2
Synonyms Ntph
Citations (0)

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Background

Tryptophan hydroxylase is the rate-limiting enzyme in the synthesis of serotonin(5-hydroxytryptamine, or 5HT). Tryptophan hydroxylase\atalyzes the biopterin-dependent monooxygenation of tryptophan to5-hydroxytryptophan(5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. Human tryptophan hydroxylase(TPH) is mapped to chromosome 11p15.3-p14 by in situ hybridization.

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$ 240.00
Cat# ABO10483
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