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Anti-TNFsR I Antibody

     
  • WB - Anti-TNFsR I Antibody ABO10740
    Anti-TNFRSF1A antibody, ABO10740, Western blottingLane 1: Recombinant Mouse TNFRSF1A Protein 10ngLane 2: Recombinant Mouse TNFRSF1A Protein 5ngLane 3: Recombinant Mouse TNFRSF1A Protein 2.5ng
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P25118
Host Rabbit
Reactivity Mouse, Rat
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 1A(TNFRSF1A) detection. Tested with WB in Mouse;Rat.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 21937
Other Names Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, TNF-R1, Tumor necrosis factor receptor type I, TNF-RI, TNFR-I, p55, p60, CD120a, Tnfrsf1a, Tnfr-1, Tnfr1
Calculated MW 50130 MW KDa
Application Details Western blot, 0.1-0.5 µg/ml, Mouse, Rat
Subcellular Localization Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane ; Single-pass type I membrane protein .
Protein Name Tumor necrosis factor receptor superfamily member 1A
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of mouse TNFRSF1A(127-141aa CKENQFQRYLSETHF), different from the related rat sequence by one amino acid.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Sequence Similarities Contains 1 death domain.
Protein Information
Name Tnfrsf1a
Synonyms Tnfr-1, Tnfr1
Function Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate- specific cysteine proteases) mediating apoptosis (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Background

Tumor necrosis factor receptor superfamily member 1A(TNFRSF1A) is a protein that in humans is encoded by the TNFRSF1A gene. The protein encoded by this gene is a member of the Tumor necrosis factor receptor superfamily, which also contains TNFRSF1B. The TNFR1 gene is mapped to 12pter-cen. it encodes a protein of 455 amino acids. This receptor can activate the transcription factor NF-KB, mediate apoptosis, and function as a regulator of inflammation.

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$ 240.00
Cat# ABO10740
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