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Anti-YIPF3 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q9GZM5 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Clonality | Polyclonal |
| Format | Lyophilized |
| Description | Rabbit IgG polyclonal antibody for Protein YIPF3(YIPF3) detection. Tested with WB, IHC-P in Human;Mouse;Rat. |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Gene ID | 25844 |
|---|---|
| Other Names | Protein YIPF3, Killer lineage protein 1, Natural killer cell-specific antigen KLIP1, YIP1 family member 3, Protein YIPF3, 36 kDa form III, YIPF3, C6orf109, KLIP1 |
| Calculated MW | 38248 MW KDa |
| Application Details | Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml, Human, Rat, Mouse, By Heat Western blot, 0.1-0.5 µg/ml, Human, Rat, Mouse |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. Cytoplasm. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Localization to the cytoplasm or to the cell membrane is developmentally and ontogenetically regulated. |
| Tissue Specificity | Expressed by nucleated hematopoietic cells (at protein level). . |
| Protein Name | Protein YIPF3 |
| Contents | Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human YIPF3(47-61aa FEDMGELHQRLREEE), identical to the related rat and mouse sequences. |
| Purification | Immunogen affinity purified. |
| Cross Reactivity | No cross reactivity with other proteins |
| Storage | At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing. |
| Sequence Similarities | Belongs to the YIP1 family. |
| Name | YIPF3 |
|---|---|
| Synonyms | C6orf109, KLIP1 |
| Function | Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Cytoplasm. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein Note=Localization to the cytoplasm or to the cell membrane is developmentally and ontogenetically regulated |
| Tissue Location | Expressed by nucleated hematopoietic cells (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLIP1(KILLER LINEAGE PROTEIN 1), also known as YIPF3. The KL1P1 gene is mapped to chromosome 6p21.1. The KLIP1 gene contains 9 exons and spans about 5 kb. And KLIP1 also contains an N-terminal signal sequence, followed by an extracellular domain, 5 transmembrane regions, and a cytoplasmic C-terminal sequence. KLIP1 expression closely correlated with hematopoietic activity in both intra- and extra-embryonic hematopoietic sites. In day 30/32 human embryo sections, KLIP1 protein expression was restricted to circulating hematopoietic cells at hematopoiesis sites. Western blot analysis of fetal liver extracts and in vitro translated KLIP1 cDNA detected the KLIP1 protein at an apparent molecular mass of 37 kD. Phylogenetic analysis indicated that KLIP1 is highly conserved.
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