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Anti-MAOB Antibody

     
  • WB - Anti-MAOB Antibody ABO10964
    Anti-MAOB antibody, ABO10964, Western blottingAll lanes: Anti MAOB (ABO10964) at 0.5ug/mlLane 1: Mouse Liver Tissue Lysate at 50ugLane 2: Mouse Lung Tissue Lysate at 50ug Lane 3: Rat Kidney Tissue Lysate at 50ugLane 4: Rat Brain Tissue Lysate at 50ugLane 5: Rat Liver Tissue Lysate at 50ugLane 6: Rat Lung Tissue Lysate at 50ugPredicted bind size: 59KDObserved bind size: 59KD
  • IHC - Anti-MAOB Antibody ABO10964
    Anti-MAOB antibody, ABO10964, IHC(P)IHC(P): Rat Liver Tissue
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q8BW75
Host Rabbit
Reactivity Mouse, Rat
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for Amine oxidase[flavin-containing] B(MAOB) detection. Tested with WB, IHC-P in Mouse;Rat.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 109731
Other Names Amine oxidase [flavin-containing] B, 1.4.3.4, Monoamine oxidase type B, MAO-B, Maob
Calculated MW 58558 MW KDa
Application Details Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml, Mouse, Rat, By Heat

Western blot, 0.1-0.5 µg/ml, Mouse, Rat
Subcellular Localization Mitochondrion outer membrane ; Single-pass type IV membrane protein ; Cytoplasmic side .
Protein Name Amine oxidase[flavin-containing] B
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of mouse MAOB (42-56aa RTYTIRNKNVKYVDL), identical to the related rat sequence.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Information
Name Maob
Function Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity).
Cellular Location Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side
Research Areas
Citations (0)

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Background

MAOB(MONOAMINE OXIDASE B), also called MAO, BRAIN, AMINE OXIDASE(FLAVIN-CONTAINING) B, is a protein that in humans is encoded by the MAOB gene. MAOB is a member of the flavin monoamine oxidase family. And it is mapped on Xp11.3. MAOB catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. Like MAOA, it also degrades dopamine. MAO-B is involved in the breakdown of dopamine, a neurotransmitter implicated in reinforcing and motivating behaviors as well as movement. MAO-B inhibition is, therefore, associated with enhanced activity of dopamine, as well as with decreased production of hydrogen peroxide, a source of reactive oxygen species.

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$ 280.00
Cat# ABO10964
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